Drug delivery by nails
Medical Research book By:Jaikumar pareta
8257 words, English
Medical > Research
ISBN: 978-131-01433-28
Nails are the hard and durable epidermal appendages structurally horny in nature. Nail plate is responsible for the penetration of the drug across it. There are number of formulations with antifungal agents viz. gels, creams and oral antifungals for the treatment of transungual infections. Among these entire nail lacquers is a new concept in treating nail infections. These nail lacquers are effective as monotherapy in treatment of superficial, distal and subungual diseases
The field of nail drug delivery following topical application is relatively young and more research in this field is needed to resolve the conflicting reports on the physico-chemical parameters that influence nail drug permeation and to find and characterize new penetration enhancers and delivery vehicles. It might be possible to include enhancers within nail lacquers.
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